neuroprotective activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7512	BMS-191011	BMS-A	Potassium Channel
	BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models		Potassium Channel
T9776	TRPM4 inhibitor 8		TRP/TRPV Channel
	TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.		TRP/TRPV Channel
T68153	Tazomeline		AChR
	Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.		AChR
T16797	RPR104632		NMDAR
	RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.		NMDAR
T27830	Lifarizine	RS 87476,RS 87476-000,RS-87476,RS-87476-000,RS87476	Calcium Channel
	Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.		Calcium Channel
T6210	Pifithrin-μ	PFTμ,NSC 303580,2-Phenylethynesulfonamide	HSP , p53 , Autophagy
	Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.		HSP , p53 , Autophagy
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T3697	3',6-Disinapoylsucrose	Disinapoyl sucrose,3,6'-Disinapoyl sucrose	BCL , Epigenetic Reader Domain
	3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.		BCL , Epigenetic Reader Domain
T21470L	Davunetide acetate	Davunetide acetate(211439-12-2 Free base)	Beta Amyloid , Microtubule Associated
	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...		Beta Amyloid , Microtubule Associated
T12617	(R)-CR8 trihydrochloride	CR8, (R)-Isomer trihydrochloride	Apoptosis , CDK
	(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1/2/5/7/9 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.		Apoptosis , CDK
T0388	Cilnidipine	FRC-8653	Calcium Channel
	Cilnidipine (FRC-8653)(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.		Calcium Channel
T8200	Ginkgolide K		AMPK , Autophagy
	Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.		AMPK , Autophagy
T73397	ENT-C225		Trk receptor
	ENT-C225 is a potent TrkB neurotrophin receptor (TrkBR) activator with neuroprotective activity for the study of Alzheimer's disease and Parkinson's disease.		Trk receptor
T3856	Tenuifoliside A		ERK , Others
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.		ERK , Others
T2423	P7C3-A20		Others
	P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.		Others
TP1079	(Arg)9 TFA (143413-47-2 free base)	Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA)	Others
	(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA (Nona-L-arginine TFA) exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.		Others
T6S2115	Ginkgolide J	BN 52024,7-beta-Hydroxyginkgolide A	PDE
	Ginkgolide J (BN 52024) has neuroprotective activity, it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.		PDE
T19812	Propentofylline	HWA-285,Karsivan,Propentophylline,Hextol,HWA 285,HWA285	PDE
	Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's d...		PDE
T23631	Adatanserin	WY-50324,WY 50324,WAY SEB 324,WY50324	5-HT Receptor
	Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of coke oven and depression.		5-HT Receptor
T125462	Gnetifolin K	GnetifolinK
	Gnetifolin K (GnetifolinK) is a novel stilbene diglucoside from Gnetum parvifolium with potential neuroprotective activity for the study of DNA damage.